Sean Miller, head coach of the University of Arizona Men's Basketball program, has played in and coached in plenty of big games.
But Saturday's battle against Pac-10 rival UCLA is the biggest one since he took over in Tucson.
Here is a preview of some of the key match-ups that will determine the outcome of this important contest.
Along with giving some basic info about each match-up, we will state who has the advantage or if it is a push (tie).
The winner of today's game will be in the conference driver's seat heading into the last week of the regular season.