"I wish the 49ers organization the best of luck during the playoffs," Edwards said in a statement on his website. "I will be working hard this off season to strengthen my knee and prepare for the 2012 season. Thanks for your continued support and for being such loyal fans."
Edwards had 15 catches for 181 yards and no touchdowns in eight games with five starts for San Francisco.
In August, the 49ers signed Edwards to a one-year deal worth $3.5 million.
Edwards had dealt with a shoulder injury and knee injury that he has fully recovered from yet.
He was inactive against St. Louis on December 4th and again for the Monday night game against the Steelers. In a loss at Arizona on Dec. 11, Edwards had no catches and expressed his surprise that he was not used more in the offense.
Edwards has to focus on getting healthy and ready for the 2012 season. I feel that he can be a contributor on a team that needs a wide receiver.
This is a loss to wide receiver that the 49ers need to find an answer to. The team is one of the worst in the NFL when it comes to scoring touchdowns in the red zone.
With the loss of Josh Morgan earlier this season to injury and Edwards now released, the 49ers will have to rely on Michael Crabtree, Vernon Davis and the rest of the wide receivers on the roster to make plays.
Based on how the season has gone for the 49ers in the red zone, it might be a short trip in the playoffs.