The Bills (5-3) are tied for first place in the AFC East, while the Cowboys (4-4) are trying to catch the New York Giants in the NFC East division. The Giants have a two-game lead coming into Week 10 action, so both teams need to win this week to remain in contention.
For the Bills, they are looking to rebound from their poorest game of the season, losing their first home game to the New York Jets. The Bills have rebounded from their earlier losses with a win, but they are only 1-2 on the road. This is the first of a key three-game road trip that will go a long way towards determining if the Bills are contenders or pretenders.
The Cowboys were hammered by the Philadelphia Eagles and then rebounded to defeat Seattle. The Cowboys defense gave up 401 yards on the ground over the past two weeks, so they will have to find a way to contain Fred Jackson and the Bills improved ground game. The Bills average 135 yards per game on the ground. Jackson is tied with Matt Forte with the most 20 plus yard rushes (10) on the season.
The Bills are No. 2 in the NFL with 15 interceptions, so Tony Romo will have to be careful with the ball, as the Bills secondary have been very quick to jump on any tipped passes or deflections at the line of scrimmage. The Bills allow the fewest sacks in the NFL, so DeMarcus Ware and company will try to determine if they can duplicate the pressure that Rex Ryan and the Jets put on the Bills last week. Word is that Rex has been on the phone with Rob Ryan this week, so anything is possible.
The Bills defense will need to try to find a way to slow down Cowboys rookie running back DeMarco Murray, who has exploded for 466 yards rushing over the past three games. With Miles Austin out due to a hamstring injury, the Cowboys will need to rely on Murray supplying more of their offense.The Cowboys are No. 31 in the NFL in red zone offense, while the Bills are tied for No. 2. That could prove to be the difference in the game.
The Bills have been able to end some nagging losing streaks this season, as they finally defeated Tom Brady and the Patriots, won a regular season game in Toronto. A win against the Cowboys and Jerry Jones would be a nice touch by the Bills and give ex-Cowboys head coach Chan Gailey a measure of revenge.
Final score: Cowboys 44, Bills 7