Philadelphia Eagles vs. Detroit Lions Betting Odds, Analysis, NFL Pick

The Philadelphia Eagles (3-0) are hoping they can pick up where they left off before their bye week when they visit the Detroit Lions (1-3) as small road favorites. The Eagles have been led by rookie quarterback Carson Wentz and first-year head coach Doug Pederson, and they will be playing their second straight NFC North opponent away from home.

Point spread: The Eagles opened as one-point favorites; the total was 46 early in the week, according to sportsbooks monitored by Odds Shark. (Line updates and matchup report)

NFL pick, via Odds Shark computer: 24.6-17.9 Eagles (NFL picks on every game)

Why the Eagles can cover the spread

The toughest part for Philadelphia here is adjusting from the role of an underdog to a favorite following a 34-3 rout of the Pittsburgh Steelers before their bye. The Eagles were four-point dogs in that game against the Steelers and three-point dogs in their previous road matchup with the Chicago Bears in Week 2, which they won 29-14 behind a strong defensive effort.

Philly has won seven of the past nine meetings with Detroit straight up, according to the Odds Shark NFL Database, and will be playing an opponent that has failed to cover the spread in nine of its last 11 games during the month of October.

Why the Lions can cover the spread

Even though the Lions have now lost three straight games, all have been decided by seven points or less, with two of those totaling a margin of four points. Detroit's 17-14 loss at Chicago was aided by quarterback Matthew Stafford's two interceptions, and the team obviously cannot continue to turn the ball over in such close games.

But the Lions have covered the spread in three of the past four meetings with the Eagles, who have also gone just 2-6 SU the previous eight times they have won consecutive games.

Smart pick

This is a tough one to call, especially since Detroit is in must-win mode at home or else head coach Jim Caldwell could be on the chopping block. The better wager involves the total, as the Lions really need a better offensive performance more than anything since that is Caldwell's specialty.

The over has cashed in each of the past five meetings between the teams and has gone 6-2 in Detroit's last eight at home, so that's the pick.

Betting trends

The Eagles are 7-2 SU in their last nine games against the Lions.

The Eagles are 1-3 ATS in their last four games against the Lions.

The Lions are 2-9 ATS in their last 11 games in October.

All NFL betting lines and point spreads data courtesy of Bleacher Report’s official odds partner Odds Shark. All quotes gathered firsthand unless otherwise noted. Check out Twitter for injury and line movement updates and Odds Shark YouTube for picks and analysis, or download the free odds tracker app.