Cesare Prandelli is without some key players for Italy's friendly with Spain in Madrid and, having called up several fresh faces, looks likely to experiment.
Both Mario Balotelli and Daniele De Rossi are out, the former through injury and the latter because he was seen punching Inter's Mauro Icardi during their recent game with Roma. Italy are also missing the injured forward Giuseppe Rossi, who had been enjoying a blistering season for Fiorentina.
Italy lost out to penalties the last time these two sides met. The Azzurri will want to up their game this time in order to beat their old rivals and set the tone for the summer and the 2014 World Cup.