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St. Louis Rams vs. San Francisco 49ers: Spread Analysis and Pick Prediction

ST. LOUIS, MO - DECEMBER 02:  Wide receiver Randy Moss #84 of the San Francisco 49ers breaks past cornerback Janoris Jenkins #21 of the St. Louis Rams during the game at the Edward Jones Dome on December 2, 2012 in St. Louis, Missouri.  (Photo by David Welker/Getty Images)
David Welker/Getty Images
OddsShark.comFeatured ColumnistNovember 27, 2013

The Rams have covered five of their last seven games against the 49ers, but they've also been shut out in two of their last four trips to the Bay Area.


Point spread: 49ers opened as 11.5-point favorites; the total was 42. (Line updates and matchup report)


Odds Shark computer prediction: 27.2-21.7 49ers


Why the Rams can cover the spread

St. Louis has won two in a row and four of its last seven games, while it has covered three of its last four. The Rams, undoubtedly under the guidance of coach Jeff Fisher, have outscored their opponents by an average of 38-15.5 in those four wins, including a 38-8 road win over the Colts.

They also bring a 5-2 ATS streak in games played at San Francisco.


Why the 49ers can cover the spread

After two trying road tripsto New Orleans and Washington D.C.the past two weeks, the Niners will be glad to be at home over the next two weeks and three of the next four. San Francisco can't afford any letdowns with the Arizona Cardinals in the mix for a wild-card berth.


Smart Pick

The Rams are the play here, as they're exuding confidence right now and will come in fired up knowing they have a chance to gain some ground on San Francisco in the NFC West. Plus, the Niners could get caught looking ahead to the Seahawks next week.



  • St. Louis is 5-2 ATS in its last seven games when playing San Francisco
    San Francisco is 15-8 ATS in its last 23 games at home
    Rams have been shut out two of past four trips here


Note: All spread and odds data powered by Odds Sharkfollow them on Twitter for injury updates and line move updates.

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