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The only thing that really matters is that the Patriots are 7-3, in first place in the division with a two-game lead. They are still in solid position to compete for a playoff bye and, with a shot at Denver in Foxborough, still hold much of their fate in their own hands.
The most looming question is at cornerback, where the Pats no longer have a starter who is healthy. They are down to Ryan and Cole, and facing Manning with those two as your starting corners is not exactly ideal.
The Patriots season could depend on getting healthy at defensive back. Will Talib ever be free of this hip ailment? Does Arrington even have a groin left to tear? There is much uncertainty, and Devin McCourty can only do so much.
The offense is showing signs of dominance again, but if the defense can't get off the field on third down, it's going to be an uphill climb every time.
If Talib can regain his early season form, Dennard bounces back from his new knee problem and Steve Gregory's thumb heals up, the Pats have a shot against anyone in the playoffs.
The only thing that's for certain is that they'll go down swinging.