Formation: 4-3-3 / 4-2-3-1
Probable starting XI: Iker Casillas; Alvaro Arbeloa, Sergio Ramos, Gerard Pique, Jordi Alba; Sergio Busquets, Xabi Alonso, Xavi Hernandez, Andres Iniesta, David Silva; Fernando Torres
Notable reserves: Pedro, Jesus Navas, Santi Cazorla, Juan Mata, Fernando Llorente, Francesc Fabregas
Spain will play just how we expect them to in defence and in midfield, but we will see a change up front.
Vicente del Bosque's system was built around David Villa and suited his strengths as a dynamic, mobile striker. His ability to drop deep or drift wide will be sorely missed and no other striker on the roster can do it to his standard.
Who starts up top for La Roja is anyone's guess.
I spoke to Diaria Vasco journalist Oier Fano (@oierfano), and he thinks Torres will start the important games, while Llorente will start the others. He was careful to outline just how important Llorente was in defeating Portugal during the World Cup 2010 and sees him as a key player.
He'll represent an aerial option if things get difficult, and the tiki-taka system Spain use has been criticised for not having a "plan B."
Oier Fano also likened a full-throttle Xavi, Iniesta and Alonso combination as "the closest thing to a Ferrari."
Overall though, we'll see a slightly toned-down version of Barcelona's dominant style of play with a direct edge if needed.