Week 13 College Football Picks: Predicting Saturday's Biggest Upsets

Johnathan CaceCorrespondent INovember 26, 2011

Week 13 College Football Picks: Predicting Saturday's Biggest Upsets

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    Thanksgiving weekend is always one of the most heated weekends in college football. It is rivalry week for most major programs, great games fill the weekend and upsets come from out of nowhere.

    When it comes to playing your rivals, anything can happen on the field. With five games between ranked opponents on Saturday, there won’t be a lull in the action all day, and the odds of an upset are through the roof.

    Here are the biggest upsets you can expect to see.

Ohio State over No. 15 Michigan

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    The Buckeyes have gotten the best of Michigan every year since 2003, and that is unlikely to change this season. It all comes down to whether Ohio State can stop Michigan quarterback Denard Robinson’s attack, and Ohio State did that in a big way last year, holding the explosive offense to just seven points.

    It will be a lower-scoring affair this season because Michigan’s defense has drastically improved from last year, but unless Robinson can figure out how to effectively throw the ball downfield against a pass defense ranked 16th in the country, don’t expect a different result.

No. 22 Notre Dame over No. 6 Stanford

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    Notre Dame does not get enough credit from the national media for what it does. If it weren’t for giving the ball away 10 times against South Florida and Michigan to start the season, this team would probably be getting a BCS bowl bid regardless of the outcome of this game.

    Stanford has given up 122 points to the three best offenses it has faced, and Notre Dame will pass over Washington to become the third-best attack. In a close game, Notre Dame makes a statement by getting a big stop late to take the Cardinal out of the running for a BCS bowl.

No. 17 Clemson over No. 12 South Carolina

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    N.C. State stunned Clemson last week, but that should only fire up the Tigers even further for their game against in-state rival South Carolina.

    The biggest key to this upset is that the Gamecocks will be without star running back Marcus Lattimore. In their only game against a ranked opponent without him, they got blown out by the passing attack of Arkansas.

    With Sammy Watkins back for Clemson, the Tigers should pick up a big win heading into the ACC Championship game.