Miami comes in at 0-7, after a tough road loss to the Giants in Week 8, while KC is still riding high after an improbable overtime win against their division rival the San Diego Chargers on Monday Night Football.
The Dolphins offense is led by journeyman QB Matt Moore, who has really struggled so far this season.
He has thrown just one touchdown and four interceptions in his three starts, while putting together a QB rating of 65.3.
This does not bode well for the Dolphins, considering the fact that the Chiefs secondary is one of their strongest units on defense.
After all, they have picked off eight combined passes in the last two games.
Miami is much more dangerous on offense when they run the ball, and former Saint Reggie Bush has a lot to do with this.
The ex-USC star has 355 rushing yards, including 103 last week against New York.
Bush and the Dolphins ground game could be their key to success against KC this weekend, due to the Chiefs having the 22nd-ranked rush defense in the league, giving up an average of 122 yards per game in that area.
When Kansas City has the ball, look for QB Matt Cassel to get the ball in the hands of his talented receiving corps that includes Pro Bowl wideout Dwayne Bowe and rookie receiver Jonathan Baldwin.
Miami is 27th in the league in pass defense, giving up around 270 yards per game to their opponents.
If the Chiefs can take advantage of this, it will be a long day for the Dolphins.
In the Kansas City running game, fourth-year RB Jackie Battle should once again get a majority of the carries this week, and he will be a load for the Dolphins defense to tackle.
On special teams, both teams have solid kickers in Miami's Dan Carpenter and Kansas City's Ryan Succop, and punters as well, with Miami's Brandon Fields and KC's Dustin Colquitt.
As for the return game, Clyde Gates is always a threat to break a long one for the Dolphins while Javier Arenas and Dexter McCluster are two very young and exciting returners for the Chiefs.
Key Matchup: Matt Cassel and the Chiefs Passing Game vs. Miami's Secondary
As I stated earlier, this will be a big key to this game for both teams.
Even though the Chiefs have stated that they are a running team in the past, they also like to throw the ball as well.
With Dwayne Bowe, Steve Breaston and Jonathan Baldwin, KC has a very talented group of wideouts, and the Dolphins secondary should have their hands full on Sunday.
Prediction: Chiefs 21, Dolphins 13
I see this game being closer than most people would think, considering that the Dolphins have been close in many of their games to this point.
In the end, the Chiefs will be too much for them at home.
Miami will have to wait at least one more week before they notch their first victory of the 2011 season.