The May 7 event will feature Pacquiao (52-3-2), the No. 1 pound-for-pound boxer in the world, going up against the former WBA super welterweight champion Mosley (46-6-1).
The reasons to purchase this card will not come from the main event, and they probably shouldn't. Fans will be treated to a fairly good undercard that may just entice them to reconsider and purchase the card for $54.99.
Prior to the Manny Pacquiao vs. Shane Mosley main event, Kelly "The Ghost" Pavlik (36-2) will make his return to the ring to face the undefeated Alfonso Lopez (21-0) in a super-middleweight bout.
After pulling out of a fight with Brian Vera in November, Pavlik entered the Betty Ford Center in Mirage, California to mend an ongoing alcohol problem that had been a problem previously in his professional boxing career. He left rehab in January.
His scheduled opponent, Lopez, has 16 knockouts in his professional career and went 11-0 over the last two years. Still untested, Lopez will be coming into the May 7 bout looking to take out one of the bigger names in the sport, even if Pavlik's recent performances haven't necessarily supported that claim.
If Pavlik is victorious, future bouts with super-middleweight stars will be offered to him, including potential opponents Carl Froch, Andre Ward and Arthur Abraham.
If Humberto Soto (54-7-2) isn't going to take a step up in competition against opponents like Juan Manuel Marquez, at least he is willing to give us good fights, which he usually does.
The WBC lightweight champion's opponent is Urbano Antillon, a fighter he fought and defeated in December 2010. It was a back-and-forth brawl and was a candidate for "Fight of the Year."
The rematch promises to be as good as the last even if the outcome is predictable.
Hopefully, a win for Soto sets him up to face the winner of Roberto Guerrero vs. Michael Katsidis or a future fight with top-five pound-for-pound fighter Juan Manuel Marquez.
In an undercard bout, former WBO world flyweight champion Jorge Arce (56-6) will be taking on the undefeated Wilfredo Vazquez Jr. (20-0-1). This super bantamweight bout will be something boxing fans don't want to miss.
Arce may be well past his prime, but he can still put on entertaining fights. His opponent is the son of boxing legend Wilfredo Vasquez Sr.
Vazquez went 3-0 in 2010, defeating Ivan Hernandez, Zsolt Bedak and Marvin Sonsona, all by knockout.
The winner of this fight may be next in line to fight WBC and WBO bantamweight champion Nonito "The Filipino Flash" Donaire.
The saying "Styles make fights" is true, but it's an intriguing argument when analyzing a possible fight between Mayweather and Pacquiao after May 7.
If anyone is giving Mosley a chance at all, it will be because Pacquiao just has an off-night.
This fight could mirror Mayweather's performance versus Mosley, but history tells us Pacquiao pulls off the victory faster and more decisively than Mayweather. He finished both De La Hoya and Hatton inside 12 rounds. Mayweather knocked out Hatton in the tenth round and won a split-decision over De La Hoya.
That doesn't mean much now, but however this fight turns out, it will become the focal point of discussions about how the two superstars match up, if they ever meet.
If Pacquiao is able to finish Mosley, something Mayweather didn't really attempt to do in their fight, he will be the first opponent to do so. It may be the only thing that convinces fans he should be in front of Mayweather on the pound-for-pound lists.
Everyone is counting the 39-year-old out, but he will still be in there fighting as if it's the last fight of his career.
If he is able to pull off the upset–no matter how–it will be the most defining moment of Mosley's extensive career.
If he isn't able to do it, well at least boxing fans are treated to a good boxing match featuring two of the best boxers of this generation.