While TMZ Sports noted that the Lakers have yet to confirm, the organization said in a letter to season-ticket holders that the Dec. 18 game would feature a "special event."
The Lakers will retire both No. 8 and No. 24, per Ramona Shelburne of ESPN.
Magic Johnson previously told ESPN it would be up to Bryant which number is retired, per ESPN (via Ryan Ward of ClutchPoints.com).
Bryant donned No. 8 from his rookie year in 1996-97 through 2005-06 before switching to No. 24 for the remainder of his career.
The 39-year-old Bryant retired at the conclusion of the 2015-16 season after a 20-year career spent entirely with the Lakers.
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Bryant was named an All-Star on 18 occasions, won five NBA championships, reeled in two NBA Finals MVP awards and was named the regular-season MVP in 2007-08.
Kobe averaged 25.0 points per game during his illustrious career, and the two-time NBA scoring champion ranks third all time in career scoring behind only Kareem Abdul-Jabbar and Karl Malone.
Bryant will join a legendary group of players to have their jersey retired by the franchise, including Abdul-Jabbar, Wilt Chamberlain, Shaquille O'Neal, Jerry West and others.