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The most important argument in favor of Francona is his success.
Yes, Francona has always been given good teams to manage. While this certainly helps, Francona's own contributions to the Red Sox should not be understated. He gave his homegrown players (Youkilis, Pedroia, Ellsbury) a chance to develop and become stars. In some cases, like sticking with Dustin Pedroia for instance, Francona was criticized at first for doing so.
But Francona stuck to his own mind, and it payed off for everyone.
Furthermore, Francona's playoff history suggests he is not just a good evaluator of talent but also a master of strategy.
In the playoffs, each win is crucial and small decisions can have huge implications. For proof, look no further than the recently finished World Series, in which bullpen management was a deciding factor. If Epstein wants to eventually create a team with perennial postseason presence, he will need a manager who can perform under October pressure. Francona looks like a good choice.
Francona's teams have excelled in the playoffs, especially once they advanced beyond the ALDS. Boston won two World Series and made two additional ALCS appearances in a seven-year span. That makes the Terry Francona era Red Sox one of the greatest teams of all time. No other available manager has a better resume in this regard.