Perhaps the two best teams in the world will face off with their contrasting styles and dominating performances both domestically and in Europe.
Bayern Munich has already mathematically clinched the Bundesliga title, while Barcelona has realistically won it with a 13-point lead over second-placed Real Madrid.
It's worth noting that in six total matches against Bayern, Barcelona has managed one win, two draws and three losses.
However, times are different, as this Barcelona has created a dynasty and will look to win their fourth Champions League title since the 2005 season.
Here are five key battles to watch out for in this clash between European giants.