Who could forget the last time these two met?
Despite being the eighth seed, the Memphis Grizzlies upset the top-seeded Spurs in 2011, and a minor rivalry has existed ever since.
Should they meet in the later rounds of the playoffs, another exciting series could be imminent.
From a positional standpoint, Memphis' greatest advantage remains the same as it was two years ago—their post tandem.
Marc Gasol and Zach Randolph form one of the league's most dominant power duos, and their supremacy proved to be the difference when these team's last met in the postseason.
Of course, the Spurs' frontcourt is much better than it was two years ago. Though Duncan is older, his production has been stronger, while Tiago Splitter has emerged as a legitimate threat.
The duties of containing Gasol and Randolph will fall to Duncan and Splitter, and if they can, the Grizzlies options are limited.
However, the true X-factor of the series will be Kawhi Leonard, the main difference between the Spurs roster of today, and that of two years ago.
Having traded Rudy Gay, the Grizzlies are weaker at the small forward position, and while Tayshaun Prince is still talented, guarding him will be easier on Leonard.
Leonard also will look to make a difference on the offensive end, with the Spurs' big men focused on Memphis' duo, while lockdown defenders, Mike Conley and Tony Allen will give the Spurs' backcourt difficulties.
Giving Leonard a chance to show his talents will be the ultimate decider, but Splitter and Duncan's jobs of containing Randolph and Gasol will be of primary importance.