Week 15 is a pivotal week for many teams that are trying to secure a playoff spot in the NFL postseason.
Several teams are looking ahead to big games or don't have as much to play for, and that could spell trouble for potential playoff teams.
Here are three teams that are on full blown upset alert for Week 15.
The Seattle Seahawks are one playoff team that is on upset alert.
They are off a dominating win against the Cardinals and will not be prepared for this game against Buffalo.
The Seahawks will have one eye on the matchup with the Week 16 Sunday Night Football game against the San Francisco 49ers. With the 49ers playing the Patriots in Week 15, the Seahawks could get into a position to take over the division.
That is if they don't take the Bills lightly.
The Birds will be distracted as they travel across the country to take on Buffalo in, of all places, the Rodgers Center in Toronto Canada.
The Seahawks are 15-33-3 against the spread (ATS) in their last 51 games following a win of more than 14 points and will be upended by a scrappy Buffalo team.
Think that is an improbable upset?
This same philosophy led to a perfect 3-0 ATS record in the Week 14 picks, which include two outright upsets!
The Bills shock the Seahawks with a big win in Week 15.
NFL Pick Against the Spread: Buffalo +5.5
Prediction: Buffalo 17 Seattle 16
The Broncos' great play of late have forced oddsmakers to set the NFL line at Broncos (-3).
The Broncos are another team traveling to the east coast and are vulnerable for the letdown. The Broncos are 6-16 ATS in their last 22 road games against a team with a winning home record and 1-4 ATS in their last five games in December.
Denver's main goal in this game will be keeping Manning healthy. This is a game the Broncos don’t need as they have a comfortable lead in the AFC West.
The Ravens are 7-3-2 ATS against teams with a winning record and get the outright victory against the Broncos.
NFL Pick Against the Spread: Baltimore +3
Prediction: Ravens 27 Broncos 17
The Packers are still banged up on defense and the secondary will have no one to properly cover Bears standout wide receiver Brandon Marshall.
Jay Cutler will be back under center and will exploit the Packers' vulnerable secondary.
Green Bay's main weakness is an offensive line that allows pressure on Aaron Rodgers all game long. The Bears will pester Rodgers causing multiple turnovers and getting a much needed win at home.
NFL Pick Against the Spread: Bears +3
Prediction: Bears 23 Packers 20