No one can really afford to lose during a UFC fight card.
From the prelim fighters getting their first shot in the promotion to the main carders struggling to stay relevant, everyone has something on the line when they step into the Octagon.
But this Saturday, nine men in particular have a lot more to lose than everyone else.
Some of them will fall out of a title hunt. Others could lose their jobs. Several can propel themselves into title contention, and one of those men is facing the hardest test of his career.
So, who has the most to lose in Rio de Janeiro this weekend?
Here's a look at the fighters who must win at all costs during UFC 153—and what happens if they fail.