Locker has been dealing with a dislocated shoulder since Week 1, and now that he's experienced a second dislocation, the inevitable result is surgery after the season.
Locker is a tough kid, but there's no way the Titans can ask him to play this week. In fact, he'll likely miss the next several games.
It's a major blow to the team, as even with the defensive struggles, they could hang their hat on Locker's growth and maturation on the field. Even in losses, the young quarterback was gaining valuable experience.
The more time Locker misses, the more the ceiling for the 2012 team drops taking with it a silver lining in the process.
These are dark days in Nashville. A win in Week 5, and all is not lost, but it's hard to imagine the team rebounding from a 1-4 start without Locker.
Jason Lisk of The Big Lead recaps Week 4.
Lisk says Jim Schwartz screwed up by punting.
Brian Burke of Advanced NFL Stats talks expected points and field position.
Peter King of Sports Illustrated praises the Texans and even a Titan in his Monday Morning Quarterback Feature.
Paul Kuharsky of ESPN.com wonders about the Jaguars' inability to stretch the field.
Alfie Crow of Big Cat Country says a fire is burning under Gene Smith's seat.
Ryan O'Halloran of The Florida Times-Union says pass protection is a problem.
Vito Stellino of The Florida Times-Union says Mike Mularkey is open to changes.
Gene Frenette of The Florida Times-Union says the line is setting back the Jaguars.
Kuharsky tells Leroy Harris that his comments were dumb.
John Glennon of The Tennessean says Tennessee is happy enough with the play of Harris.
Stephanie Stradley of The Houston Chronicle recaps a blowout win.
Tania Ganguli of The Houston Chronicle says teammates couldn't keep J.J. Watt off the highlight film.
John McClain of The Houston Chronicle says Quintin Demps has a broken arm.
McClain says the Texans want answers in the run game.
Phil B. Wilson of The Indianapolis Star says Pat Angerer missed the game when he was out.
Reggie Hayes of The News-Sentinel has video of Colts players reacting to news about Chuck Pagano.
Gary Varvel of The Indianapolis Star has the best possible response to the news about Pagano's cancer.
Wilson says it's just not fair.
Bob Kravitz of The Indianapolis Star assures us that Pagano will be back.
Mike Chappell of The Indianapolis Star says Bruce Arians was emotional.