Jim Wyatt of The Tennessean tweeted that he thinks Locker's return to the game is unlikely:
Locker's return is questionable. I wouldn't expect to see him again today for #Titans
— Jim Wyatt (@jwyattsports) Sept. 30, 2012
Locker first injured his shoulder in the Titans' Week 1 loss to the New England Patriots, and he's been wearing a brace on his left shoulder ever since. The official injury was a dislocation.
This injury is likely tied to the previous problem, as Locker was sacked by Glover Quin and immediately held his left shoulder in pain.
Veteran Matt Hasselbeck took over for Locker on the Titans' next series.
Fantasy owners shouldn't be affected greatly, as Locker is owned in just 15.6 percent of ESPN leagues and is starting in less than five. He's a backup fantasy quarterback who would only start in desperation matchups or in injury situations.
That said, Locker's ownership went up almost 10 percent after he threw for 378 yards and two touchdowns against the Detroit Lions in Week 3. Expect him to be dropped in as many leagues following this week, regardless of the severity of the injury.
For the Titans, however, Locker's injury represents a nagging problem for the progression of their franchise quarterback. Hasselbeck is a capable backup and not a significant drop-off talent-wise, but Locker is playing because the Titans are buying into the young quarterback as their leader of now and the future.
Not having Locker on the field only saps the team of valuable learning opportunities.
The length of Locker's injury is another thing to consider here. One could assume that Locker will miss a couple weeks, especially after re-injuring a previous shoulder problem. The Titans likely will want to be careful that the shoulder heals before Locker is back on the field.
Having Hasselbeck around should make that an easy choice.
Overall, we won't know how bad this injury is until later next week. Locker is currently undergoing X-rays in the Titans locker room.
The injury isn't a big blow fantasy-wise, but the Titans will want their young quarterback back on the field as soon as possible.