In the much-anticipated rematch of Super Bowl XLII, Manning again got the best of the NFL's brightest quarterback star, Tom Brady, and the New England Patriots.
Manning's first-quarter touchdown pass to Victor Cruz gave the Giants an early lead, and after falling behind 17-9 just after halftime, he again brought New York back from the brink of disaster.
Behind Manning's passing, the Giants recorded a pair of third-quarter field goals to cut the Pats lead to just two.
And with 3:46 remaining in the fourth quarter, the Giants defense forced a stop, putting the ball in Eli's hands. He completed 5-of-6 passes for 81 yards and drove the Giants near the New England goal line, allowing Ahmad Bradshaw to score the go-ahead touchdown.
But in another strange case of history repeating itself, it was Manning's miraculous 38-yard completion along the sideline to Mario Manningham (a la David Tyree's helmet catch four years earlier) that set up the game-winning score.
Manning completed 30-of-40 passes for 296 yards and one touchdown to earn the game's MVP, becoming just the fifth player (Tom Brady, Terry Bradshaw, Joe Montana, Bart Starr) to win a pair of Super Bowl MVPs.