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The lone offensive player to make the list, Steelers WR Mike Wallace would be the NFL's best choice for a player who could race Usain Bolt (but he'd still get burned).
Wallace is a speedy WR who averages almost 17 yards per reception. Cleveland DB Joe Haden will have his hands full unless the Browns decide to double-cover Wallace (which should be the gameplan).
This is the deal-breaker for either team in the game. As long as the Browns offense doesn't turn the ball over and Mike Wallace is completely isolated by double coverage, then it's gonna be a nail-biter.
In terms of the double coverage on Wallace, the Browns must jam him at the line of scrimmage and keep a safety over the top. The longer it takes Wallace to get down field (even if it's an additional second), the better odds of Cleveland getting a sack or forcing a turnover.
However, with other solid receiving targets in Hines Ward, Antonio Brown, and TE Heath Miller, Cleveland must have a perfect gameplan. Both Ward and Miller are capable of beating single coverage, so the Browns must choose when they double Wallace wisely, otherwise it's touchdown-city.
That being said, watch to see how much attention (or lack thereof) Cleveland gives to Wallace, as well as whether they decide to let Joe Haden cover him mono-e-mono. Either way, Wallace's production is a focal point in this game.