Arsene Wenger picked a full strength side with the first-choice attacking triumvirate of Robin van Persie, Gervinho and Theo Walcott in attack, while Laurent Koscielny returned at right-back.
Wigan started the contest brightly and had a great chance early on to open the scoring as Jordi Gomez saw his shot deflected wide, but that was about it as far as their goalscoring chances went for the entire match.
Arsenal struggle through the first quarter of the game to fashion any chance of note but were gifted the lead when Mikel Arteta's long range strike somehow evaded goalkeeper Ali Al-Habsi and ended up in the back of the net.
Just moments later Thomas Vermaelen headed in a second goal and the next 45 minutes were a walk in the park for the Gunners as they netted further goals through Gervinho and Robin van Persie without Wigan being remotely close to getting back into the game.
Here are the Arsenal players' ratings from the win at the DW Stadium.