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Antonio Margarito being hit by Shane Mosley
Cotto vs. Margarito II was originally to happen during the summer of 2009, only a year removed from the original 2008 blockbuster fight until Margarito was caught with plaster in January 2009 during the Mosley fight.
This led to a one-year suspension leading to Cotto taking alternative opponents and not being able to immediately set things right against Margarito.
While Margarito was suspended, Cotto struggled against Joshua Clottey to earn a split decision and was stopped in the final round against Manny Pacquiao.
Some say Cotto was not the same man after Margarito has beat him. If Cotto had gotten his rematch and gained revenge, at least some if not all of his confidence could have been restored.
That means the old Cotto would have been available to possibly beat Clottey more convincingly and eke out a win against Pacquiao. The world will never know thanks to Margarito. Cotto will make him pay for it.