This injury knocked him out of the game and may result in him missing an extended period of time. If that's the case, then the Rams and their quarterback Sam Bradford will need to dig deep to find a receiver to replace his production.
This isn't as hard as it seems, however. Amendola is listed on the Rams' depth chart as the No. 2 behind starter Brandon Gibson. Without Amendola, this means that Gibson's time on the field will be increased.
While Gibson does not have the same type of elusive speed as Amendola, he is a veteran commodity and will prove to be highly valuable to the Rams with Amendola injured.
Another option is Danario Alexander, the backup to the other starting Rams receiver Mike Sims-Walker. Alexander isn't a poor choice to step onto the field in Gibson's place, based on the offensive situation.
While the loss of Amendola is a major blow to the Rams offense, it is something from which they can recover. Their other receivers certainly have the talent, and it's just up to them to use it.