There are no ranked team-vs.-ranked team matchups this weekend, but there are a few possible upsets out there.
I'll take a look at every game involving a Top 25 team this week, except for No. 12 Oklahoma State, who played on Thursday, and No. 6 Boise State, who plays tonight (Friday) and is already featured in my Friday Night Predictions article.
I'll also show you some intriguing non-Top 25 matchups that could end up being fun games.
Minnesota (6-5) at No. 15 Iowa (9-2), Noon ET/11 AM CT, ESPN (HD)
Point Spread: Iowa -11
Iowa's dream season has imploded in the span of two weeks. Sitting pretty at 9-0, Hawkeyes quarterback Ricky Stanzi went down for the season against Northwestern, who handed Iowa their first loss, 17-10.
Iowa gave a strong fight last week to Ohio State before finally falling in overtime, 27-24. As much as Minnesota will want to take the Floyd of Rosedale, this won't be the time for it to happen.
Prediction: Iowa 30, Minnesota 10
No. 9 Ohio State (9-2) at Michigan (5-6), Noon ET/11 AM CT, ABC (HD)
Point Spread: Ohio State -12
Nearly everyone's already handed this one to Ohio State before it's even been played, and I don't blame them. Michigan's defense has looked absolutely horrendous all season long, save for about three games, and the offense has not been all that great either.
Still, Michigan knows what's at stake here: a chance to ruin a good buzz for Ohio State heading into the Rose Bowl and an opportunity to make themselves relevant again in the best rivalry in college football.
While I do expect Michigan to play fairly well in this one, I just don't see the upset happening.
Prediction: Ohio State 24, Michigan 19
Duke (5-5) at No. 21 Miami (FL) (7-3), Noon ET/11 AM CT, ESPNU (HD)
Point Spread: Miami (FL) -19
While you can't pass over the incredible story that is Duke football in 2009, you have to recognize the fact that it is Duke. As great as Thaddeus Lewis has been this year, he won't be able to throw all over the Canes.
Expect Duke to play hard and play tough, though. They'll be in it in the fourth quarter, but the Canes will get a insurance score late to secure the victory.
Prediction: Miami 31, Duke 21
Chattanooga (6-4, FCS) at No. 2 Alabama (10-0), 12:20 PM ET/11:20 AM CT, SEC Network for some
No point spread
Oh, good grief. I know Tide fans are rejoicing at the thought of a good tuneup for Auburn, but this one could be over at the end of the first quarter.
Prediction: Alabama 59, Chattanooga 7
Florida International (3-7) at No. 1 Florida (10-0), 12:30 PM ET/11:30 AM CT, ESPN-Game Plan/PPV (FL)
Point Spread: Florida -45
See Chattanooga-Alabama. The only interesting thing to see here is if Tebow comes out after a quarter or at the end of the first half.
Prediction: Florida 70, Florida International 10, Tebow comes out of the game after one quarter because the score's 35-0
Memphis (2-8) at No. 24 Houston (8-2), 1:00 PM ET/Noon CT, CSS
Point Spread: Houston -23.5
Houston laid a massive egg vs. Central Florida last week, losing 37-32 and giving the Knights their first win ever against a Top 25 school.
Expect Case Keenum and company to come in tomorrow angry and ready to take it out on anything. Expect that anything to be Memphis.
Prediction: Houston 62, Memphis 24
No. 4 TCU (10-0) at Wyoming (5-5), 2:00 PM ET/1:00 CT, The Mtn. (HD)
Point Spread: TCU -31
No one's even giving Wyoming a chance to come off of their own field alive, much less have any opportunity of a shot at winning this game.
The Cowboys will score a garbage touchdown or two late in the game to make it look slightly better, but the Horned Frogs will thoroughly dominate this one.
Prediction: TCU 52, Wyoming 17
Air Force (7-4) at #19 BYU (8-2), 3:30 PM ET/2:30 PM CT, CBS College Sports
Point Spread: BYU -10
Last season, Air Force led one-loss BYU at halftime 14-10 and looked to have a shot at an upset before BYU took over in the second half, outscoring them 28-10 en route to a 38-24 victory.
Air Force hasn't forgotten about that game and surely had this one circled on their calendars at the start of the year.
BYU will score a touchdown in the final two minutes of play to win this one and run their winning streak over Air Force to six in a row.
Prediction: BYU 21, Air Force 17
No. 17 Wisconsin (8-2) at Northwestern (7-4), 3:30 PM ET/2:30 PM CT, Big Ten Network (HD)
Point Spread: Wisconsin -7
Why must a game as good as this be relegated to the Big Ten Network while Virginia at Clemson somehow sneaks onto ABC/ESPN?
I know ESPN probably didn't want to seem too impartial to the Big Ten, but come on. Northwestern's already pulled off one good upset this season against Iowa, and I think good upset No. 2 will come tomorrow.
Prediction: Northwestern 20, Wisconsin 17
No. 10 LSU (8-2) at Ole Miss (7-3), 3:30 PM ET/2:30 PM CT, CBS (HD)
Point Spread: Ole Miss -4
Pre-game, the big story here is the announcement by the Mississippi charter of the Ku Klux Klan that they will be outside the stadium at the game in protest of Ole Miss banning the song "From Dixie With Love" because of Rebels fans chanting "the South will rise again."
In-game, it will be interesting to see how Jordan Jefferson plays after being out for half of the Alabama game and the entire Louisiana Tech game with a sprained right ankle.
LSU wants revenge after getting smoked at home by Ole Miss last year and I believe they'll get it.
Prediction: LSU 27, Ole Miss 20
North Carolina State (4-6) at No. 16 Virginia Tech (7-3), 3:30 PM ET/2:30 PM CT, ESPNU (HD)
Point Spread: Virginia Tech -21
This is NCSU's last stand to make a crazy run to a bowl game like they did last year. Russell Wilson has basically been the entire team this season.
Virginia Tech's just here to pad their win total and for Ryan Williams to take the Hokies' I'll take V-Tech, but expect NCSU to give them a good game.
Prediction: Virginia Tech 31, NCSU 19
No. 25 Rutgers (7-2) at Syracuse (3-7), 3:30 PM ET/2:30 PM CT, ESPN360
Point Spread: Rutgers -8.5
Rutgers has been a great success story this season, rebounding from a humiliating opening-week 47-15 loss to Cincinnati and winning seven of their last eight.
Syracuse's Greg Paulus, the flopper-turned-quarterback, has had a season where his rustiness has showed. After playing four years of basketball at Duke, he decided to play one year of football for the Orangemen and it hasn't worked out so well.
While he'll want to give it his best shot for 'Cuse's final home game, they won't have much of a shot against a great Scarlet Knights team.
Prediction: Rutgers 34, Syracuse 10
No. 13 Penn State (9-2) at Michigan State (6-5), 3:30 PM ET/2:30 PM CT, ABC/ESPN (HD)
Point Spread: Penn State -3
Penn State is already assured of not making the Rose Bowl, so they're hoping for a win versus Michigan State and an Iowa loss to have any hopes at all of a BCS at-large bid or to be able to slip into the Capital One Bowl.
Michigan State is just looking to better their bowl selection and can do so with a big win over the Nittany Lions here.
With a great chance to wreck the remaining BCS (and possibly Capital One Bowl) hopes that Penn State has, I'll take Michigan State in a thriller.
Prediction: Michigan State 20, Penn State 13
Virginia (3-7) at No. 18 Clemson (7-3), 3:30 PM ET/2:30 PM CT, ABC/ESPN (HD)
Point Spread: Clemson -21
Virginia is having an awful year and Al Groh could be gone at the end of the season. In contrast, Clemson's having a pretty good year and looks to be headed to a good bowl game.
As much as Virginia will want to play hard in this one, they have no shot.
Prediction: Clemson 45, Virginia 14
San Diego State (4-6) at No. 23 Utah (8-2), 4:00 PM ET/3:00 PM CT, Versus (HD)
Point Spread: Utah -20
San Diego State is looking to win out and possibly make a bowl game. Utah's looking to rebound after an embarrassing 55-28 loss to No. 4 TCU last week. Although Utah will have a slight letdown, I'll still take them.
Prediction: Utah 31, SDSU 21
No. 20 Oregon State (7-3) at Washington State (1-9), 5:00 PM ET/4:00 PM CT, TBA
Point Spread: Oregon State -31
Alright, it's time for our weekly blowout roll call!
Eastern Michigan? Here!
Western Kentucky? Here!
Washington State? Present and head of the class!
Prediction: Oregon State 49, Washington State 10
California (7-3) at No. 14 Stanford (7-3), 7:30 PM ET/6:30 PM CT, Versus (HD)
Point Spread: Stanford -7.5
Stanford shot way up in the rankings after their blowout win on the road at now former Pac-10 king USC and it's a rare feeling for Stanford fans to head into the 112th Big Game as the favorite.
However, don't doubt Cal will come out and want to shorten Stanford's series lead. Without Jahvid Best though, I just don't see it happening.
Prediction: Stanford 34, California 20
(Game of the Week) No. 11 Oregon (8-2) at Arizona (6-3), 8:00 PM ET/7:00 PM CT, ABC/ESPN (HD)
Point Spread: Oregon -6.5
In what is considered a must-win game for both teams, and, therefore, my Game of the Week, Oregon has a chance to clinch at least a share of the Pac-10 title, while an Arizona victory can give the Wildcats a chance at their first Rose Bowl in program history.
It's literally one of those games where you kind of don't want to see either team lose because of the potential possible for this game.
The last time Oregon went on the road against a tough Pac-10 team, they were smoked by Stanford. I'm using that same logic in this pick.
Prediction: Arizona 34, Oregon 31
Kansas (5-5) at No. 3 Texas (10-0), 8:00 PM ET/7:00 PM CT, ABC/ESPN (HD)
Point Spread: Texas -28
The big storyline for this game is Kansas coach Mark Mangino, who has been accused of having extreme anger management issues, rumors supported by former players coming out and speaking about the Double Chin's "hurtful" remarks towards said players.
Even though he's basically raised Kansas football from the dead, he is on the chopping block and could be out the door if he loses this one by more than a couple of scores.
Texas won't cover the spread, but they'll still handily beat an overmatched Kansas team.
Prediction: Texas 41, Kansas 17
Games Outside of the Top 25 to Watch
North Carolina (7-3) at Boston College (7-3), Noon ET/11 AM CT, ESPN2 (HD)
Point Spread: Boston College -3
Both of these teams have had quite surprising records and both are headed to bowl games. This should be a pretty fun game to watch, even if it is low-scoring. I'll take Boston College in a close one.
Prediction: Boston College 20, North Carolina 14
Oklahoma (6-4) at Texas Tech (6-4), 12:30 PM ET/11:30 AM CT, FOX Sports Net
Point Spread: Oklahoma -6.5
Oklahoma has sputtered this year with Sam Bradford being out and Texas Tech just hasn't been the same without a great receiver like Michael Crabtree and a great quarterback like Graham Harrell.
It really could be called the Disappointment Bowl. I have a feeling we're going to see a great game, though. This one will come down to the final few plays and I'll take Texas Tech in a shootout.
Prediction: Texas Tech 42, Oklahoma 38
Connecticut (4-5) at Notre Dame (6-4), 2:30 PM ET/1:30 PM CT, NBC (HD)
Point Spread: Notre Dame -6
Notre Dame is coming off a tough 27-22 loss at Pitt. UConn's in the midst of an incredibly tough year with the loss of starting cornerback Jasper Howard's life to a stabbing.
For UConn, this is an opportunity to win one for Jasper, as the floundering Irish are playing as uninspired as they have all year. I'll take UConn in the semi-upset.
Prediction: Connecticut 24, Notre Dame 21
Well, those are my predictions for this week. I guess I'll see how I did next week. Let's hope for another good week of college football!
Questions and comments are always welcome.