Heyneke Meyer will seek to see his South Africa side open the floodgates in South Africa's 2014 Rugby Championship opener against Argentina, as they need to take advantage of their home fixture against Argentina.
New Zealand's meeting with Australia in Sydney may garner most of the Week 1 attention but for the Springboks to stage any genuine bid to dethrone the All Blacks, a strong showing is needed against the Pumas.
Daniel Hourcade, meanwhile, is simply aiming to reverse the disappointments of previous years, his side still having yet to see their first Rugby Championship win, with viewing information and key player predictions discussed in more detail ahead.
Date: Saturday, August 16
Time: 4:05 p.m. BST/11:05 a.m. ET
TV Info: Sky Sports 2 (UK), SuperSport 1
Key Players To Watch
South Africa: Handre Pollard
A bright career with the Boks' youth divisions has swiftly paved the way to senior honours for fly-half Handre Pollard, whom Meyer has placed his faith in at No. 10 for Saturday's clash.
The playmaker might be young, but a starting spot ahead of Morne Steyn is no small feat, and Jon Cardinelli of the Financial Mail says he's every bit deserving of the place:
This year has been one of immense growth for the 20-year-old, showcasing his ability to not just be a weapon with his feet or as a running asset but as a combination of the two who can potentially reign in the position for a decade or more.
South Africa will be looking to use their outside backs in excess this weekend, fighting against Argentina's yearning for territory in the most direct fashion they know.
However, Pollard brings an air of unpredictability to the role, and while his duty as a catalyst to the likes of Jean de Villiers and Damian de Allende will be crucial, his individual threat with ball in hand makes him the man to watch in Pretoria.
Argentina: Juan Martin Fernandez Lobbe
Hourcade's loose forwards stand among the Pumas coach's strongest gems, and after missing the first two rounds of the 2013 Rugby Championship, Juan Martin Fernandez Lobbe will be as keen to make an impact as any.
The Toulon staple plays a vital role in Saturday's trip to Loftus Versfeld, where he'll look to combat the strength of opposing back-row figure Francois Louw.
And it's this battle that SA Rugby magazine sees as being especially important to the result, pointing out the head-to-head as their Duel of the Week:
For the Pumas to retain the possession necessary for victory, Lobbe must ensure the Springboks' terriers are prevented from getting a hold on the dog-work, but his individual responsibilities will be far greater.
Argentina will also be relying upon their openside to have a telling impact around the fringes, he is one of the genuine stars of their roster who has his work cut out for him in all aspects of play, both attacking and defensive.