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Where have we seen this before?
Aside from 25 minutes at the end of Manchester City's Champions League clash with Real Madrid last season, the last time these two met was World Cup 2010.
Gareth Barry was left rather humiliated on that occasion, left for dead as Mesut Ozil launched several incisive breaks for the victorious Germans.
Fast forward to the present day and each have been key figures for their new sides, integral to the impressive starts of both Everton and Arsenal.
Who emerges best out of their direct clash will have a large bearing on the result.
If it's Barry, then Arsenal will lose an element of their fluidity. Their passing won't be as slick as Ozil is cramped for room and sees his input become sparser. It would also lead to several breaks from the Toffees with Arsenal players caught up field.
However, if it's Ozil then Everton are in danger of being overrun in the final third. Without a protective shield, the likes of Phil Jagielka and Sylvain Distin will be pulled around leaving ample space for the Gunners to exploit.
The Toffees would also lose their own dictator on the ball and would struggle to retain possession.
This promises to be the marquee clash of this game.