The Jayhawks confusing overtime defeat to Michigan in Friday's Sweet 16 game spurred talks of recent demoralizing defeats to the likes of VCU, Northern Iowa and others.
These tough losses have ended All-American careers, diminished coaching legacies and halted potential NCAA tournament runs. Some have come at the hands on unknown double-digit seeds, while others have come to No. 1 seed, eventual national champions.
Historic programs cringe at any loss, favored or unfavored, Final Four or opening round.
As Naadir Tharpe's desperation heave at the buzzer clunked off the backboard, memories of Ali Farokhmanesh, Shaka Smart, Juan Dixon and Cuttino Mobley run once again as we look at the toughest losses in Kansas history.