Let's be honest here, England shouldn't have too much trouble dispatching San Marino. The real questions will be asked when Roy Hodgson's team take on Group H leaders Montenegro in Podgorica just four days later.
Montenegro were ranked 117th in the FIFA international ranking system in 2009. In four short years they have jumped almost 100 places to 28th. England, for their part, were ranked ninth in 2009 and are now classed as the fourth best team in the world.
During the same period, San Marino have dropped from 201st to 207th.
They are the joint-worst team in world football with the Turks and Caicos Islands.
Roy Hodgson could pick a team from this article's readers and still be confident of a victory.
Much as we would like that, it isn't a luxury he can afford. Momentum and giving experience to youngsters who will play a key part in his Brazil 2014 squad are a must.
With that in mind Hodgson can experiment somewhat, but he will still want to keep the same nucleus together for that all-important showdown in Montenegro.
Here, Bleacher Report looks at Picking the Best England Starting Lineup to Take on San Marino, with a view to facing Montenegro 96 hours later.
Ben Foster , Joe Hart, Fraser Forster.
Leighton Baines, Gary Cahill, Ashley Cole, Jolean Lescott, Steven Caulker , Glen Johnson, Chris Smalling, Kyle Walker.
Michael Carrick, Tom Cleverley, Steven Gerrard, Frank Lampard, James Milner, Leon Osman, Scott Parker , Alex Oxlade-Chamberlain, Ashley Young.
Jermain Defoe, Wayne Rooney, Daniel Sturridge, Daniel Welbeck, Theo Walcott.