(UPDATE, 5:15 ET: According to Howard Fendrich of the Associated Press, the Eagles are calling McCoy's injury a concussion.)
If a concussion is the diagnosis, rookie running back Bryce Brown will become a must-own for Week 12.
McCoy, who carried 15 times for 45 yards and caught six passes for 67 more, took a helmet-to-helmet hit late in Philadelphia's 31-6 loss to the Washington Redskins Sunday. The Eagles were also without quarterback Michael Vick Sunday because of a concussion he suffered in Week 10.
According to Howard Fendrich of the Associated Press, a cart was needed to remove McCoy from the field.
Judging by the replay, chances are McCoy will be diagnosed with a concussion. Per NFL concussion rules, McCoy would then be subjected to the independent testing next week to determine if he can play in Week 12 against the Carolina Panthers.
If he can't, Brown will be the go-to man at running back for the Eagles.
Brown, a 21-year-old undrafted rookie, carried five times for 35 yards against the Redskins and has 141 total rushing yards this season. However, his value will skyrocket if McCoy is ruled out against the Panthers.
Owned in under one percent of ESPN leagues currently, Brown would take over a large role in an Eagles offense that may continue leaning on the run without Vick healthy. Philadelphia was forced to abandon the run Sunday after the Redskins jumped out to a big lead.
No matter the format or size, Brown should be added early next week—especially for owners of McCoy. He's a valuable handcuff who can put up starting-caliber numbers if McCoy is lost for a week or more down the stretch.