Cavaliers quarterback Michael Rocco hit tight end Jake McGee for a 10-yard touchdown with just six seconds on the clock as Virginia came back from a 10-point deficit to beat Miami, 41-40.
With the loss, the Hurricanes will now need to beat Duke if they want a shot to play for the ACC Championship.
It was the same old story for the Hurricanes as the defense continued to struggle, allowing 482 yards of total offense to the Cavaliers.
Miami fell to 5-5 (4-3 ACC), while Virginia stands 4-6 (2-4 ACC).
Here are the winners and losers for the Hurricanes in the loss against the Cavaliers.