For all the promise they showed in the second half, the damage was done in a lackluster first half when they allowed Tottenham to race into a 2-0 lead.
Man U Manager Sir Alex Ferguson had made it clear that he will not tolerate slip-up's in Europe this season, so this is a fixture United will have targeted as three points.
For Cluj, this is their Champions League final. The day they welcome a European giant to their stadium, is one in which they will not just roll over and accept defeat.
Here are six predictions of how the action will unfold in Dr. Constantin Radulescu Stadium.