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Mayweather stopped Manfredy in the second round.
With his first world championship in the bag, the level of competition for Floyd Mayweather Jr. inevitably began to rise. He would defend his WBC super featherweight championship successfully eight times.
No. 19: Angel Manfredy (WBC Super Featherweight Championship)
Dec. 19, 1998
Angel Manfredy was a top contender in the 130-pound division who hadn't lost a fight in four years and was coming off the biggest win of his career, an eighth-round TKO of Arturo Gatti, earlier that year.
Mayweather blitzed Manfredy and knocked him out in dominating fashion in the second round.
No. 20: Carlos Alberto Ramon Rios (WBC Super Featherweight Championship)
Feb. 17, 1999
Rios certainly had enough names. But he didn't have nearly enough skill in the ring to defeat Floyd Mayweather. He did, however, extend him the full 12 rounds for the first time in his career losing a unanimous decision by scores of 120-109, 120-110 and 119-108.
No. 21: Justin Juuko (WBC Super Featherweight Championship)
May 22, 1999
Juuko was a solid power-puncher from Uganda. But Mayweather was in another league, stopping him by ninth-round TKO in his third defense of his 130-pound title.
No. 22: Carlos Gerena (WBC Super Featherweight Championship)
Sept. 11, 1999
Gerena was in his second attempt to win the WBC 130-pound title, having lost to Genaro Hernandez in 1998. He was at least competitive against Hernandez. He lost every round to Floyd Mayweather Jr. en route to a corner stoppage in the seventh round.
No. 23: Gregorio "Goyo" Vargas (WBC Super Featherweight Championship)
March 18, 2000
Vargas was a former WBC featherweight champion who fought hard against Mayweather. He just didn't have the speed or firepower to compete with someone on that level. This is the famous fight where Mayweather turned from the action in the 10th round to correct Jim Lampley's declaration that he had turned southpaw twice in the fight.
Vargas was down in the sixth round and lost a unanimous decision by scores of 119-108 twice and 118-109.
No. 24: Emanuel Augustus
Oct. 21, 2000
Don't let his record fool you. Augustus was widely considered one of the toughest guys in boxing to fight. He's fought virtually everyone—check out his record—and more often than not gives a good accounting of himself.
Before facing Miguel Cotto this year, Floyd Mayweather frequently referred to Augustus as his toughest opponent. And Mayweather did what he does—he won, by ninth round TKO. But it wasn't easy or pretty.