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GK: David de Gea
David de Gea was left out of the Liverpool starting lineup but should return in goal for United, continuing Sir Alex Ferguson's policy of not sticking with one goalkeeper.
LB: Alexander Buttner
Sir Alex handed Alexander Buttner his debut in place of Patrice Evra against Wigan Athletic but brought the Frenchman back into the fold against Galatasaray and Liverpool.
The manager may decide to give his new signing another opportunity to get some experience.
RB: Rafael da Silva
Ever since Rafael was handed the No. 2 jersey, his form has dramatically improved.
His forward runs and goals (surprise!) have inspired United to wins of late and he should start this game.
CB: Jonny Evans
Sir Alex Ferguson confirmed that Nemanja Vidic's absence in the Liverpool game was a precautionary measure because the Serb was feeling "a bit tight around the knees" [The Daily Mail].
Evans to take Vidic's place.
CB: Rio Ferdinand
With Chris Smalling and Phil Jones out with injury, Rio Ferdinand is unlikely to be rested for this one so I see him starting against Newcastle.