Tonight marks the first primetime game the Carolina Panthers have played in almost two years. It also marks the first time star quarterback Cam Newton has played under the bright lights of Bank of America stadium.
The last primetime game the team played was in December of 2010, where the Steelers handed them a sound 27-3 thrashing.
Eli Manning is coming off a career-high 510 yards passing last week against the Tampa Bay Buccaneers.
Two elite quarterbacks and the whole nation watching should make for a pretty high flying showdown.
Here are some keys to the game if the Panthers want to send the defending Super Bowl champions back to New York with a loss.