Savannah State went 1-10 to finish last in the Mid-Eastern Athletic Conference last season, while Oklahoma State went 11-1 en route to a wild Fiesta Bowl victory over Stanford.
Needless to say, these are two teams on very different playing fields as we enter their Week 1 tilt.
Nonetheless, it's football. The Cowboys will want to make sure they are ready for Arizona in Week 2, and the Tigers will try to retain some semblance of pride.
Let's take a look at this chapter of college football's opening week.
When: Saturday, September 1 at 7 p.m. ET
Where: Boone Pickens Stadium in Stillwater, Okla.
TV: Fox College Sports
Radio: Cowboy Radio Network (Oklahoma State) and 90.3 FM (Savannah State)
Live Stream: OKState.com
Betting Line: TBA
What's At Stake?
Oklahoma State enters this season with last year's success in mind. Its No. 19 preseason ranking is because of a few important losses on both sides of the ball, but it still has the talent to compete in the Big 12.
Saturday's game is the first step toward that success.
The Cowboys currently have five ranked teams on their season slate. That makes winning in a game like this that much more important.
The Tigers don't have as much at stake because their expectations are significantly lower. In a game like this, the underdog squad must do their best to keep the game close.
Savannah State enters Oklahoma State's house and the 60,000-plus people in Boone Pickens Stadium will be charged up. They must keep their emotions at bay and start off on the right foot as they try to improve on their one victory from last season.
Oklahoma State Player to Watch: Wes Lunt, QB
Lunt will do his best to replace Brandon Weeden's 4,328 yards and 34 touchdowns from last season as a true freshman in Mike Gundy's pass-happy attack.
Rivals.com ranked Lunt as the No. 7 pocket-passing quarterback coming out of high school this season. This Week 1 matchup is an ideal way for him to get his feet wet at the college level.
The Cowboys' success this season rides almost solely on Lunt's shoulders. He will have help from running back Joseph Randle's 1,000-yard legs, but a lot will be expected from the freshman signal-caller.
Oklahoma State throws the ball early and often. Their offense is fun to watch, and watching Lunt operate the controls in his first season will make them even more intriguing.
All eyes in Stillwater will be on this young arm as he tries to establish himself as a passing force in the Big 12.
Savannah State Player to Watch: Leroy Cummings, DL
It's hard to find a bright spot on a one-loss team, but Cummings was extremely productive as a freshman last year.
He racked up 28 tackles (9.5 for a loss), six sacks and also forced a fumble.
Cummings stands 6'2'', 270 pounds. He can line up in multiple spots, and he will play a huge role in making sure Lunt doesn't have time to find an open man.
If you watch one Tigers player on Saturday, keep an eye on their sophomore pass-rusher. He will be the one wreaking havoc in the backfield.
Matchup to Watch: Antonio Bostick vs. Cowboys' Corners
Bostick's job may be on the line for Savannah State in this one. According to the team's website, backup quarterback Victorian Hardison is making himself a major contender at this point.
The Tigers' starter will really feel the heat in this one. Not only is his team overmatched, but he's facing two of the best corners in the country in Brodrick Brown and Justin Gilbert.
The two Cowboys' corners combined for 10 interceptions last season. As a team, Oklahoma State surrendered nearly 27 points per game.
If they want to turn that around this season, it all starts on the perimeter. Brown and Gilbert will get their first test against Bostick as he tries to hand onto the starting job.
Oklahoma State 42, Savannah State 6