Van Persie, 28, has made it clear that he would like to leave the Emirates in order to challenge for trophies. Arsenal have endured a surprisingly baron spell over the last 6 years, failing to win any trophy.
The Dutchman had a superb season for the Gunners last term, scoring 30 goals in 38 Premiership games.
He did they have a poor Euro 2012 tournament as Holland fell at the group stage after a string poor performances.
Van Persie would be somewhat of a gamble for any of the interested sides, as he's had a poor run with Injuries in the past and has missed a lot of playing time during his eight years with Arsenal.
Arsene Wenger will be reluctant to sell to either of the Manchester clubs as Arsenal look to challenge for the Premier League title in the coming season.
Even more so City than United as he has lost a number of key players to Roberto Mancini’s men in the last couple of summer transfer windows, including Samir Nasri and Kolo Toure.
Van Persie, on the other hand may also be reluctant to move over to Italy and Juventus as Seire A is nowhere as strong as it has been in the past and Italian sides have failed to make an impact in Europe over the last couple of seasons.
Personally, I think he will end up at City, but I am not sure if he is really needed at the Etihad with likes of Sergio Aguero and Carlos Tevez already staking claim for a starting spot.
Where do you think van Persie will sign, or do you believe he can be persuaded to remain a Gunner for another season?
One thing is for sure though; Arsenal will be a much weaker side without him. Mr Wenger must be really getting fed up of his stars deserting season after season, and something has to change at the Emirates. Otherwise, Arsenal will become nothing more than a feeder club in the future.