Arena's men are boosted with the prospects that Robbie Keane will return to the lineup after a rather terrible campaign with the Republic of Ireland at Euro 2012.
Los Angeles are currently 5-8-2 and take on a Vancouver team that is coming off a 1-1 draw to the New York Red Bulls at home.
Kickoff is scheduled for 7:30 p.m. PT/10:30 p.m. ET, and will be televised by KDOC and KWHY. Here are 10 bold predictions ahead of Saturday's tilt.