Now the Spurs are not only riding a 19-game win streak, but also are a combined 33-5 on the season at the AT&T Center (including playoffs).
If the Thunder plan on heading back home with the series even, several things must get better for Scott Brooks' team in Game 2.
Here's a quick look at how Oklahoma City can steal Game 2.
James Harden Getting to the Free-Throw Line
Harden has struggled of late, shooting only 37 percent from the floor his past six games, but he somehow found a way to not once get to the charity stripe in Game 1.
He's lived at the line during the postseason, getting there an average of 7.1 times per game, but his lack of aggressiveness in Game 1 resulted in no free throws.
That has to change.
Russell Westbrook Being More Efficient
Guarded by Tony Parker, Westbrook struggled in Game 1, shooting only 7-of-21 for the night. In addition, he had only five assists and turned the ball over four times.
Westbrook has to get the ball moving against the Spurs' aggressive defense and that means more than just passing it to Kevin Durant.
Score in the Paint
San Antonio's defense did a great job of collapsing and making it tough for the Thunder to score inside, but Oklahoma city can not turn themselves into strictly a jump-shooting team.
The Thunder struggled to score inside all night long, as the Spurs enjoyed a 50-26 advantage in points in the paint. Oklahoma City missed 20 of their 33 shots in the lane and where outscored 16-2 in the paint during the game's final quarter.
Four Quarters of Defense
Through three quarters, the Thunder did a very good job defensively, but they made it easy on San Antonio in the fourth, allowing 39 points in that quarter alone.
That marked only the second time all season long that Oklahoma City has allowed 39 points in any quarter, the first time being when they allowed 39 to the Sacramento Kings in the first quarter on April 24th.
Despite finishing the night with 11 steals and nine blocks, the Thunder allowed San Antonio to shoot 75 percent from the floor during the fourth quarter and that can't happen anymore.
Manu Ginobili torched the Thunder for 26 points on only 14 shot attempts in the series' opener and the Spurs' bench outscored the Thunder's 52-37.
Granted, the Spurs are a very deep team, but if San Antonio's bench scores that much and there's that much discrepancy between the two benches, this will become a short series.
Oklahoma City shot 42 percent from the floor in Game 1, down from the 46 percent they shot during the regular season, but the Thunder's Big Three combined to shoot only 39 percent on the night and Kevin Durant went without a field goal in the fourth quarter for the first time in his postseason career.