The Oakland Athletics and Seattle Mariners play two games at the Tokyo Dome in Japan, the first on Wednesday, to open the 2012 Major League Baseball season.
The trip to Tokyo comes nine years after the 2003 trip between Oakland and Seattle was cancelled due to complications involving the conflict in Iraq.
Since then, the New York Yankees and Tampa Bay Devil Rays (now "Rays") faced off in Japan in 2004, and Oakland "hosted" the Boston Red Sox on the other side of the Pacific Ocean in '08.
But those weren't the first times the MLB has played games outside of the U.S. and Canada.
And it's not the only sport to do so.
This is a look back at the best regular-season games played in other countries by the major sports leagues.