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Notre Dame includes many institutions as traditional rivals, but the University of Michigan is perhaps the most hated of them all.
Some may claim that USC earns that distinction, but it's truly a personal choice.
The Wolverines have had Notre Dame's number as of late, winning the previous three matchups against the college football behemoths.
Last season's contest, a thrilling 35-31 Michigan victory that went down to the wire, only added to the insurmountable hate that Fighting Irish fans have for the Wolverines.
All in all, the annual meeting with Michigan is circled on the calendars of Notre Dame Nation.