In the ups and downs of college football, upsets and blowouts are an inevitability. This means that entire seasons can be decided by the outcome of a single game.
If a team fails miserably in a season opener, their hopes of making the National Championship game are completely gone and the odds of even making a respectable bowl game are diminished.
It isn't always an early win or loss that tells what a team is made of, it's how they respond after they see how they've performed thus far.
Even if a team pulls off a win, a performance not up to par with their ranking could raise questions about the direction of the program. Thus, it is up to the team and the coaching staff to answer those questions before they lose their ranking, their support in the media or even their hopes of a successful season.
Here are five college football teams, in no specific order, with the most to lose as the rest of the season progresses.