This one happened on January 3, 2003. One of the most unforgettable sports injuries of all time came in one of the most exciting games of all time.
Miami and Ohio State were locked in a battle for the National Championship, and Willis McGahee had already ran for 67 yards and a touchdown in a stellar performance.
Then early in the fourth quarter tragedy struck. On a screen pass, Willis McGahee was hit in the knee, bending it backwards. This caused him to tear his ACL, MCL, and PCL, all major ligaments. Ohio State went on to defeat Miami in double overtime 31-24.
McGahee was considered a guaranteed top-five pick up to this point, and he was ultimately picked 23rd overall by the Buffalo Bills. After extensive surgery and rehabilitation he was able to play again.