The non-BCS leagues found no success in last year's BCS, watching their lone representative, Northern Illinois, flounder against Florida State in the Orange Bowl.
Still, the No. 1 overall pick, Eric Fisher, came out of Central Michigan.
The left tackle soared up draft boards and was taken by the Kansas City Chiefs, becoming the first non-BCS player to claim that spot since Alex Smith in 2005.
The only other offensive tackles to ever go No. 1 went to USC (Ron Yary), Ohio State (Orlando Pace) and Michigan (Jake Long)—three of the most esteemed programs in college football history.
Who else is ready to shatter the mold this season? Check out the list, which is listed in alphabetical order.
Note: Notre Dame and BYU were both excluded from the list for playing as Independents.