There is no such thing as a sure thing in college football, but there are always some games that look like locks.
With this week's slate of games featuring so many matchups between BCS Top 25 teams, there will certainly be some top-tier action this weekend.
Fans of these teams should come out of Saturday smiling, as these teams are virtual locks to win weekend .
No. 2 Florida over No. 10 Georgia
We have learned a lot about both of these teams in recent weeks.
We learned that Georgia lives and die by Aaron Murray and that when he's pressured, Georgia loses. Getting after Murray was the key to South Carolina's 35-7 victory over the Bulldogs.
Florida, meanwhile, has the trappings of an elite team. The offense is 25th in the nation in rushing, while the defense gives up a mere 12.1 points per game.
Florida has all the pieces in place to take over this game. The Gators running game is dominant enough to take advantage of Georgia's mediocre run defense, which gives up 167.9 yards per game.
On the other side of the ball, Florida has an even better defense than the South Carolina unit that gave Aaron Murray fits. The Gamecocks set out the blueprint for stopping Georgia, so expect Florida to follow it well.
Both teams are talented, and this might be close, but Florida looks like a good lock to win the game.
Spread: Florida (-6.5) over Georgia
No. 3 Oregon over Colorado
Another year, another top-10 Oregon offense. Redshirt Freshman Marcus Mariota has the offense flying high on the ground and through the air, while the defense has been stingy, giving up just 20.1 points per game.
The closest game the Ducks have had all year was a 17-point victory over Fresno State. Their average margin of victory has been approximately 30 points per game, showing just how dominant this Oregon team is.
Meanwhile, Colorado is 1-6 and struggling to salvage a season already lost. The Buffaloes are averaging just 18.7 points per game while surrendering 42.6 points per game.
Today, Colorado faces its toughest test of the season, while Oregon should be able to give its starters some rest early in this one. Expect a massive blowout.
Spread: Oregon (-47) over Colorado
No. 1 Alabama over No. 11 Mississippi State
Not often would a victory by a No. 11 team be considered a monumental upset, but such is Alabama's dominance that no one ever expects the Tide to lose.
Just look at the stats. Alabama gives up just 8.3 points and 195.6 yards per game. Opponents have averaged 1.9 yards per rush against the Crimson Tide defense, while their secondary has given up just two passing touchdowns while collecting 14 interceptions.
Offensively, Bama is nearly as strong. The Tide average 41 points and 439.6 yards per game, with running backs Eddie Lacy and T.J. Yeldon providing one of the best one-two punches in the nation.
This is not to take away from anything that Mississippi State has done this season. The Bulldogs have earned an undefeated season thus far and have often won in convincing fashion.
Unfortunately, Mississippi State has yet to take on a ranked team. Alabama is far and away the toughest test the Bulldogs will have faced, and they just aren't up to it.
Expect a big Alabama victory.
Spread: Alabama (-23) over Mississippi State
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