With conference play now hitting full stride, Week 6 of the college football season features some key league matchups that are the best we have seen all season.
The weekend slate offers 22 of the AP Top 25 in action, and five games with Top 25 teams playing one another. We have finally made it past the point where there are cupcake games with no odds to choose from.
Without question the most intriguing games of the week can be found in the SEC, as Georgia travels to South Carolina and LSU will be in Gainesville taking on Florida.
Among the other must-see games in Week 6 are West Virginia at Texas, Nebraska at Ohio State and Washington at Oregon.
Predicting the winner of a game is one thing, but choosing the winner against the spread is a completely different story. Here is an analysis and prediction of all the Top 25 college football matchups against the spread.
*All times Eastern; odds via Sportsbook.ag