It happens like clockwork, year after unforgiving year. Groups of unsuspecting fans watch as their team's season—their hopes, their dreams, their delusions of grandeur—goes up in a fulminating puff of smoke.
Even if there's no Appalachian State in this year's bunch (though there's plenty of FBS teams playing ranked opponents), there's a cadre of unranked upstarts who could pilfer a win from a team with a 5-point-font number next to their name.
And in the spontaneously combustible world of college football, one game is enough to derail an entire season.
Here are five ranked favorites who should be on upset alert in Week 1 of the college football season.