Everything you thought you learned during the preseason, just throw it out the proverbial window.
For much of the NFL, the status quo seemed to be in play, as the Detroit Lions still made boneheaded mistakes, quarterbacks Tony Romo and Eli Manning both seemed determined to underachieve and the Jacksonville Jaguars looked as offensively inept as Peyton Manning and the Denver Broncos looked automatic.
Where the NFL surprised was where things deviated from the norm. The Oakland Raiders looked like they had some life in Week 1. Tom Brady and the New England Patriots looked listless. Minnesota Vikings running back Adrian Peterson was bottled up for much of his afternoon.
In Week 2, all eyes will be on the NFC West as the Seattle Seahawks and San Francisco 49ers face off. The Seahawks will look to overcome a slow start on offense, while the 49ers will try to avoid cooling off against their divisional foe.
Other fantastic matchups include the Washington Redskins at the Green Bay Packers, the "Manning Bowl" as Peyton and Eli face off and an AFC North slobberknocker as Pittsburgh faces Cincinnati.
All those picks and more are just a few clicks ahead. Disagree with our picks? Make yours in the comments below.
All betting lines are from Bovada (via ESPN) and are intended for informational purposes only. All picks are straight-up.