B/R Consensus Pick: Pick'Em (6-6)
Schottey: Colts, 16-10
The Colts offense is floundering without Reggie Wayne, and the Cardinals defense is legit. Yet, in the end, I believe a whole lot more in Andrew Luck than in Carson Palmer.
Bowen: Cardinals, 26-20
The Colts and Andrew Luck won't be able to put together another comeback win against the Cardinals defense out in the desert.
Schalter: Cardinals, 20-17
Indianapolis is a better team overall, but the Colts' current receiving corps against the Cardinals secondary is not a good matchup. Donald Brown and Trent Richardson will have a tough time against the Cards front seven, too.
Freeman: Colts, 24-21
Andrew Luck will outplay Carson Palmer in this matchup.
Miller: Colts, 31-24
Traveling to Arizona isn't easy, but the Colts know Cardinals head coach Bruce Arians and will be ready for his deep passing attack. Also, betting against Andrew Luck is a bad idea.
Frenz: Cardinals, 28-20
The way the Colts have played over the past few weeks, it's a small miracle that they have managed to get to 7-3. Luck will have to perform better against the blitz, and without Reggie Wayne as an outlet, it's hard to envision that happening. Look for Bruce Arians to test the Colts defense deep.
Hangst: Colts, 20-17
Miraculous fourth-quarter comebacks are not a good offensive strategy, and trying to do that on the road is even more difficult. However, the Cardinals are no more remarkable of a team than the Titans, who the Colts managed to beat in a come-from-behind victory last week. Better yet would be Andrew Luck working his magic earlier than the game's final 15 minutes.
Hansen: Colts, 24-21
The Colts are a little tough to figure out, but as long as Andrew Luck is under center, they will be fine. I don't trust Carson Palmer to win big games against tough opponents.
Bardeen: Colts, 24-21
Neither Donald Brown nor Trent Richardson are going to be able to get too much going on the ground against an Arizona defense that allows just 81.4 rushing yards per game. That’s OK, though, as Andrew Luck is ready to take over.
Gagnon: Cardinals, 24-17
The rest of the league has figured the young and wild Colts out. If you can barely get past Tennessee and get crushed by St. Louis, I'm not giving you a victory over a hot Cardinals team on the road.
Langland: Cardinals, 27-20
Ever since Reggie Wayne landed on injured reserve, Andrew Luck has had trouble finding consistent playmakers outside of T.Y. Hilton. I would have never imagined saying this prior to the season, but the Arizona Cardinals are a more talented football team than the Indianapolis Colts with six weeks left to play.
Kruse: Cardinals, 30-23
Indianapolis has lost its edge since the bye. Bruce Arians will make another slow start hurt, as the surging Cardinals will win their fourth straight.