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This tandem is essentially a poor man's version of the Nowitzki/Howard pairing.
The way Dwight Howard and Chris Bosh would play as teammates is how I envision Howard and Nowitzki playing together. Bosh is a finesse power forward just like Nowitzki is, except he lacks the shooting range and strength that his theoretical counterpart has.
Throughout his career, Bosh has played next to the likes of Rasho Nesterovic, Andrea Bargnani and Joel Anthony at center—not nearly the guys you want going to war with you in the paint. Other centers he has been next to include Jermaine O'Neal, Erick Dampier, Zydrunas Ilguaskas and Jamaal Magloire. All of these guys were in later stages of their careers when they were with Bosh. But even in their heyday, they did not equal the presence of Dwight Howard down low.
Putting them together would finally give Bosh that guy—he has always needed someone else in the paint to take pressure of of him.
Howard is the perfect candidate. He can focus on the dirty work, while Bosh continues his mid-range game without the same kind of defensive attention on him.
A Bosh forced to do heavy, physical work is a less effective one. Howard would allow him to stay in his comfort lane.